Table of contentsTversky Shape Clustering for Screening Data Outline PowerPoint Presentation Symmetry vs Asymmetry Asymmetric Measure Defined Tversky Measure For Shape Example Shape Comparison with Tversky Slide 8 Slide 9 Slide 10 Slide 11 Asymmetric Taylor Non-Disjoint Version Slide 13 Slide 14 The Conformer Problem – Finding a Needle in a Haystack Modules in Action Calcium Ion Channel Actives Flexibility of Calcium Ion Channel Active Ligands Representative Shapes for Calcium Ion Channel Ligands – Symmetric Clustering Results Flexible Calcium Ion Channel Ligands Hits Against Representative Compounds – Symmetric Results Calcium Ion Channel Ligands – The Numbers Representative Shapes for Calcium Ion Channel Ligands – Asymmetric Clustering Results Flexible Calcium Ion Channel Ligands Hits Against Representative Compounds – Asymmetric Results The HIV-RT Experiment Flexibility of HIV-RT Moderately Active Ligand HIV-RT Highly Active Ligands Hitlist Results Example of Highly Active HIV-RT Ligand Hit Russian Doll Teaser Acknowlegments |
Author: Norah and John Maccuish |