---
title: "miniWebinar Series: Billions Scale Virtual Screening in Orion®"
description: "On-demand webinar \"Billions Scale Virtual Screening in Orion®\" presented by Mark McGann, Senior Principal Scientific Developer at OpenEye, Cadence Molecular Sciences."
---

[On-Demand Webinars ](https://www.eyesopen.com/webinars/recordings)

# [miniWebinar Series: Billions Scale Virtual Screening in Orion®](https://www.eyesopen.com/webinars/recordings/billions-scale-virtual-screening-in-orion)

 Written by [OpenEye Scientific](https://www.eyesopen.com/webinars/recordings/author/openeye-scientific) | Apr 3, 2024 6:33:50 PM

 

This session's speaker was Mark McGann, Senior Principal Scientific Developer at Open Eye, Cadence Molecular Sciences. Mark holds a bachelor's degree and a Ph.D. in chemical engineering, proceeding to focus on developing virtual screening tools. He laid the foundations of the FRED and HYBRID docking programs from 1998 to 2000 while working on his post-doc under Frank Brown at Johnson&Johnson. Mark joined OpenEye in 2000 and continued to develop those tools. Since then he has worn many hats at OpenEye and currently develops and maintains Orion’s suite of ultra-large virtual screening floes.

About this session

This session was focused on FastROCS, GigaDock, and AI-optimized GigaDock Warp floes for screening billions of molecules among 250+ floes available in Orion®. With the available ready-to-search commercial compound library collections in Orion®, one can easily search and analyze more than 12 billion stereo-enumerated commercially available compounds.

- FastROCS™: 3D shape similarity search at the speed of 2D similarity search
- Gigadock™: Fast, robust, and comprehensive docking solution - when you need the most rigorous results
- Gigadock™ Warp: A smart combination of docking (FRED and HYBRID), shape similarity (FastROCS™), and machine learning models

 

[View full post](https://www.eyesopen.com/webinars/recordings/billions-scale-virtual-screening-in-orion)

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