---
title: Shape-based Methods in Virtual Screening and Lead Hopping Webinar
description: "Join us for our webinar \"Shape-based Methods in Virtual Screening and Lead Hopping\" presented by Paul Hawkins, Ph.D., Applications Science Group Leader from OpenEye."
---

[On-Demand Webinars ](https://www.eyesopen.com/webinars/recordings)

# [Shape-based Methods in Virtual Screening and Lead Hopping Webinar](https://www.eyesopen.com/webinars/recordings/shape-based-methods)

 Written by [OpenEye Scientific](https://www.eyesopen.com/webinars/recordings/author/openeye-scientific) | May 1, 2013 4:00:00 AM

Join us for our webinar **"Shape-based Methods in Virtual Screening and Lead Hopping" **presented by Paul Hawkins, Ph.D., Applications Science Group Leader from OpenEye.

This webinar was originally held on **May 1, 2013**. Access the on-demand recording below.

*In this webinar we will cover:*

- [ROCS](https://www.eyesopen.com/rocs) as a shape-based similarity tool
- ROCS for virtual screening: 
    - The definition of a suitable null model for ROCS in VS and comparison of ROCS’ performance versus that null model.
    - The successful application of ROCS to virtual screening problems with a varying levels of available structural information using published data.

- ROCS for alignment

- The GUI for ROCS, vROCS.

- The successful application of ROCS to virtual screening problems with a varying levels of available structural information.

[View full post](https://www.eyesopen.com/webinars/recordings/shape-based-methods)

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