OpenEye hires talented people that fit into our idiosyncratic culture. Candidates that believe they have the right stuff are encouraged to apply.
OpenEye Scientific Software provides software to the Pharmaceutical Industry for molecular modeling and cheminformatics. It has done so since 1997 in its continuing mission to provide novel software, new science and better business practices to the industry. Central to our approach is the importance of shape and electrostatics as primary variables of molecular description, platform-independent code for high-throughput 2D and 3D modeling, and a preference for the rigorous rather than the ad hoc.
With offices in the United States, Germany & Japan, OpenEye Scientific Software is a global company. We offer a unique working culture. We believe that work should be fun and our working environment supports this philosophy. OpenEye Scientific Software is a recipient of the Santa Fe 2017 Small Business of the Year Award, as well as a 4-time recipient of the When Work Works Award for workplace flexibility, formerly known as the Alfred P. Sloan Awards for Business Excellence.
Location:Santa Fe, New Mexico
Education: Master's or PhD in Computer Science, Chemistry or closely related field
Experience: 3+ years
Travel: Occasional
Manage Others: No
Job Description:
OpenEye Scientific Software is seeking a talented and enthusiastic person to join the rapidly-expanding Customer Support Group as a Scientific Integration Engineer. Reporting to the VP of Global Support, your main directive will be to help our customers customize and maximize their experience on OpenEye's new, state-of-the-art, cloud-based CADD platform, Orion. Working closely with the chemists, med-chemists and modelers that use Orion, you will take advantage of OpenEye's extensive and proven Cheminformatics and Modeling toolkit libraries to develop custom, large-scale, highly-parallelizable workflows in Orion that fully leverage the power of the cloud. Additionally you will aid customers in linking their internal resources, both compute and databases, to the Orion platform. Your efforts in providing custom solutions to our customers will help drive their drug discovery efforts forward.
OpenEye Scientific will not provide work visa sponsorship for this position. Please apply only if authorized to work in the U.S.
Requirements:
What you have:
- Master's or PhD in Computer Science, Computational Chemistry, or closely related field.
- 3+ years extensive experience using Python.
- Strong background in cheminformatics or closely related field.
- Good people/communication skills
What we prefer:
- Strong ability to work as a member of a team
- Experience with technologies such as SQL, REST APIs, Docker
- Familiarity with Python packages such as pandas, scipy etc.
- Desire to help customers solve complex problems
- Desire to learn new ideas and technologies
- Knowledge of the computer-aided drug design (CADD) pipeline
OpenEye offers a competitive salary and exceptional benefits. Just to name a few:
Flexible working schedule
This job posting is for a position at our headquarters in Santa Fe, NM. This location has the added benefits of:
Application Contact Information:
To apply please Email cover letter and resume to: hr@eyesopen.com
No calls or walk-ins, please.
OpenEye Scientific Software is an Equal Opportunity Employer
Date Posted: July 2020
Location:Boston, MA
Education: Master's or PhD in Computational Chemistry, Cheminformatics, Structural Biology, or related field required
Experience: 5+ years in a pharmaceutical, biopharmaceutical or computational chemistry environment
Travel: Yes (up to 25%)
Manage Others: Yes
Job Description:
We seek an Associate Group Head to join our high-growth scientific software and technology company. The successful candidate will have knowledge of both computational chemistry and cheminformatics software and the scientific rationale behind the design and use of the technology. Examples of such applications are, but not limited to, small molecule docking to protein receptors, free energy calculations using molecular dynamics approaches, support for structure-based design tools, 2D and 3D similarity calculations, QSAR approaches, etc. Experience with high-performance computation, e.g. via Cloud computing, is essential. The successful candidate will report to the Head of the Application Sciences and Services Group.
Responsibilities:
Requirements:
The successful candidate will work independently, be self-motivated and take initiative. The position requires highly effective communication skills and the ability to work cooperatively with staff inside and outside of the group.
Employment location is at the Boston OpenEye corporate office. Position will require periodic travel to other OpenEye locations, conferences, company meetings and customers.
Application Contact Information:
To apply please Email cover letter and resume to:
hr@eyesopen.com
Or mail to:
OpenEye Scientific Software Recruiting
9 Bisbee Court, Suite D
Santa Fe, NM 87508
No calls or walk-ins, please.
OpenEye Scientific Software is an Equal Opportunity Employer
Date Posted: 06/09/2020
Location:Santa Fe, New Mexico
Education: Bachelor's degree
Experience: 1+ year of relevant experience
Travel: Minimal
Manage Others: No
Job Description:
You will be working in our Cloud Operations group to aid the day to day operations required for our cloud-native SaaS platform for computer-aided drug design, Orion. Orion is built leveraging many AWS products and services including: CloudFormation, EC2, S3, RDS, ElastiCache, ELB, CodePipeline, IAM, KMS, CloudWatch, Lambda, ECS, ECR, Elasticsearch Service, SES, SQS, SNS, Step Functions, VPC, Route 53 and Athena. Our infrastructure as code is managed through thousands of Linux EC2 instances using Ansible as our configuration management tool. We use Python and Boto 3 as our default to build related tooling. See a snapshot of our infrastructure from our 2016 AWS re:Invent talk.
You will join our growing Cloud Operations group working in our dedicated space, Ops Center, at our Santa Fe HQ, while also interacting with our CI development, backend and frontend teams. In addition to supporting our internal Orion users you will interact with Fortune 500 companies who are running Orion working with colleagues in our customer service team to help provide an outstanding support experience.
Day to day tasks will include managing deployments for the many installations of Orion, assisting internal developers with AWS issues and handling service desk requests for account management and other admin-level operations. You will join other Cloud Operations group members participating in on-call rotations, which will include occasional out of business hours rotations as well.
OpenEye is not providing work visa sponsorship for this position. Please only apply if eligible to work in the U.S. and will not require work visa sponsorship in the future.
OpenEye offers a competitive salary and exceptional benefits. Just to name a few:
Requirements:
The following are a plus, but not required:
Experience with customer service tools (e.g. Jira Service Desk, Opsgenie, Statuspage, etc.)
Application Contact Information:
To apply please Email cover letter and resume to:
hr@eyesopen.com
Or mail to:
OpenEye Scientific Software Recruiting
9 Bisbee Court, Suite D
Santa Fe, NM 87508
No calls or walk-ins, please.
OpenEye Scientific Software is an Equal Opportunity Employer
Date Posted: 05/15/2020
Location:Santa Fe, New Mexico
Education: B.S. in Computer Science or equivalent experience
Experience: Various. 3+ years in a senior developer or architect role for the Senior Developer position
Travel: Occasional
Manage Others: No
Job Description:
You would be working as a member of the backend team, responsible for developing OpenEye’s cloud platform, Orion. This platform is a state of the art elastic workflow scheduler and orchestration system. Backend developer responsibilities include designing database models, and creating APIs to allow scientists to leverage the cloud without needing to be experts in distributed systems.
Orion is a container-based scientific workflow system written in Go and Python. While there are some interesting workflow and container orchestration systems out there, none deliver the flexibility in using legacy applications and toolkits, ease of use, scalability, and reliability that we are targeting. Our system is made up of Floe, a Python workflow framework, and a cloud-based workflow runtime and user interface leveraging many technologies, including Django, Docker, and AWS.
More about Orion and the science being done on it:
https://www.youtube.com/watch?v=gjKNHK4jWMQ
Below is a summary of a few of the scientific problems being solved with Orion:
Molecular Dynamics
Crystal Structure Prediction
The largest molecular Docking calculations ever run
Large Scale Virtual Screening (FastROCS)
Requirements:
The following are a PLUS, but not required:
Application Contact Information:
To apply please Email cover letter and resume to:
hr@eyesopen.com
No calls or walk-ins, please.
OpenEye Scientific Software is an Equal Opportunity Employer
Date Posted: 04/21/2020
Location:Santa Fe, New Mexico
Education: BS in Computer Science or equivalent experience
Experience: 5+ years relevant experience
Travel: Occasional
Manage Others: No
Job Description:
OpenEye is looking for an expert in Infrastructure Automation who has experience with Continuous Integration Systems (CI/CD). As a Linux aficionado and automation guru, you will use tools such as Ansible and Python/Bash Scripts to automate and perfect repetitive processes. You will be responsible for growing and maintaining OpenEye’s existing CI infrastructure which includes over 40 Ubuntu, CentOS, MacOS, and Windows systems. As a member of the Systems Administration team, you will share management responsibilities for the core network systems including DNS, LDAP, NFS, etc.
This position requires the ability to interpret many project requirements into reliable and maintainable solutions. The ideal candidate will have a strong desire to automate, incorporate security in every aspect of their work, and always consider how their efforts today contribute to the larger design goals.
Primary Duties include:
OpenEye is not providing work visa sponsorship for this position. Please only apply if eligible to work in the U.S. and will not require work visa sponsorship.
Requirements:
The following are a plus, but not required:
OpenEye offers a competitive salary and exceptional benefits. Just to name a few:
This job posting is for a position at our headquarters in Santa Fe, NM. This location has the added benefits of:
Application Contact Information:
To apply please Email cover letter and resume to:
hr@eyesopen.com
Or mail to:
OpenEye Scientific Software Recruiting
9 Bisbee Court, Suite D
Santa Fe, NM 87508
No calls or walk-ins, please.
OpenEye Scientific Software is an Equal Opportunity Employer
Date Posted: 02/03/2020
Location:Santa Fe, New Mexico
Education:
Experience:
Travel: no
Manage Others: No
Job Description:
Our internship programs provide students with an interest in computer science an opportunity to apply the knowledge they learned in a classroom into real life problems. While basic computer skills are required, we are also looking for students who study biology, chemistry or physics.
Our 2020 Internship projects are posted below. To apply for any of these positions: Email your resume and a cover letter to hr@eyesopen.com. * In your cover letter please include:
1) The project for which you are applying,
2) Why you are interested in that particular project,
3) The dates that you are available for a Summer internship.
4) Whether you will require housing accommodations (pay rate is lower if we provide housing).
5) Let us know if you are currently authorized to work in the U.S.
We look forward to hearing from you!
Project #1: Weighted Ensemble Simulations for Ligand Unbinding *** THIS PROJECT HAS BEEN FILLED ***
Location: Santa Fe, NM Mentor: David LeBard, Senior Scientific Software Developer
Goal:
The aim of this project is to develop an automated algorithm applying the path sampling technique known as the weighted ensemble method to calculate ligand unbinding kinetics. Unbinding kinetics (i.e. ligand residence times) is important to the pharmaceutical industry because it measures how long a potential drug will reside within a protein’s active site, which under the view of the drug-target residence-time model will dictate the pharmacological activity. However, unbinding kinetics are difficult to predict computationally, since system sizes are large, and timescales of the unbinding processes are orders of magnitude outside the range of classical simulations. Therefore, this internship will be focused on exploring aspects of weighted ensemble simulations to provide an efficient means of overcoming the large free energy barriers associated with ligand unbinding in a short amount of wall-clock time.
Job Description:
OpenEye Scientific is seeking a graduate-level intern to explore various aspects of ligand unbinding using the weighted ensemble (WE) method. This project will involve (but is not limited to) building a workflow to automate the setup of the WE simulations of ligand unbinding, as well as a separate workflow to analyze the mechanism, pathway, and kinetics of the ligand unbinding process. All WE simulations will be run using WESTPA with OpenMM as the molecular dynamics (MD) engine. This project will be conducted using OpenEye’s cloud platform for scientific computing.
Experience required:
Preferred Skills:
Key Learnings:
Project #2: Cloud Ops - Automated Resource Management *** THIS PROJECT HAS BEEN FILLED ***
Location: Santa Fe, NM Mentor: Alex Hamilton, DevOps Engineer
Job description:
OpenEye Scientific is seeking an intern to continue work on automated resource optimization and management. This includes utilizing various Amazon Web Services and Python code. You will be tasked with building a system for managing Trusted Advisor alerts and automating their resolution.
Applications are not limited to Computer Science majors. A willingness to learn is crucial as you are not expected to be an expert in all areas.
Experience required:
Preferred skills:
Key learnings:
Project #3: Optimization with Reinforcement Learning (Scientific Software Developer) **** THIS PROJECT IS FILLED *****
Project #4: Backend Web Developer Intern *** THIS PROJECT HAS BEEN CANCELLED ***
Project #5: Inventory Management Specialist *** THIS PROJECT IS POSTPONED UNTIL FURTHER NOTICE ***
Location: Santa Fe, NM Mentor: Nick Sewell, Head of Information Technology
Goals:
The goal of this internship is to implement an Asset Inventory System, collect and record hardware and support information for existing hardware, and develop the process for registering new equipment and tracking the usage through its lifecycle.
The products generated by this internship will allow the IT team to better manage existing hardware. Additionally, the Finance team will be able to use this data to track hardware depreciation schedules as well as have a structured basis for total hardware valuations.
Job Description and Requirements:
OpenEye is seeking an intern to work as an Inventory Management Specialist. During this internship you will work with the Head of IT to design and implement an asset inventory system to track OpenEye's growing list of hardware. This project will include collating data, creating organization structures and processes for managing a diverse collection of hardware.
The ideal candidate for this internship will be an expert in organization with a keen attention to detail. You should be process driven and take great pride in designing processes and systems which are easy for other people to use. You will be challenged with a variety of tasks and problems so the ability to research, evaluate and adapt possible solutions is crucial. You should be proficient with Microsoft Excel and general usage of a computer. You do not need to be an expert in IT, but familiarity with the components of computer and network systems is beneficial.
Applicants from all majors are accepted.
Requirements:
Application Contact Information:
To apply please Email cover letter and resume to:
hr@eyesopen.com
The cover letter may include your GitHub username (or a sample of your code), if available.
Or mail to:
OpenEye Scientific Software Recruiting
9 Bisbee Court, Suite D
Santa Fe, NM 87508
No calls or walk-ins, please.
OpenEye Scientific Software is an Equal Opportunity Employer
Date Posted: 04/01/2020
