Search Billions of Available Compounds, Fast!

The Orion® Commercial Compound Library Collection

Making Your Large-Scale Virtual Screening Faster and Easier

Orion® provides a single point of access to commercial vendors’ libraries, making your large-scale virtual screening faster and easier.

You no longer need to access different vendors’ sites or manually process their data. Orion does the work for you! Libraries are processed in Orion, letting you quickly perform structure-based and ligand-based searches by 2D, 3D shape (FastROCS), and 3D docking (Gigadock™).

Through Orion, you can search over 4 billion stereoenumerated molecules and 40 billion conformers. This means you could identify promising drug-like molecules from billions of compounds in as little as 30 minutes and at a fraction of the cost of in vitro high-throughput screening assays.

Available Databases

OpenEye maintains and updates the following libraries so that you will always have ready access within Orion.

Enamine REAL

  • 3.6 Billion Stereoenumerated Molecules

WuXi GalaXi

  • 1.07 Billion Stereoenumerated Molecules

Mcule Ultimate

  • 158 Million Stereoenumerated Molecules

Disclaimer: Commercially available vendor databases will be updated in Orion periodically based on content availability from those vendors. With each database update, the previous version will be retained for three months, after which it will be removed from Orion access. Neither the availability of these vendor databases nor the compounds in them within Orion constitute or imply endorsement or recommendation by OpenEye Scientific.

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